linker dna造句
例句与造句
- The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.
- In chromatin neighboring nucleosomes are separated by the linker DNA and in many cases also by the linker histone H1 as well as non-histone proteins.
- This involves the wrapping of DNA around nucleosomes with approximately 50 base pairs of DNA separating each pair of nucleosomes ( also referred to as linker DNA ).
- Despite gaps in our understanding, a general model has emerged wherein H1 s globular domain closes the nucleosome by crosslinking incoming and outgoing DNA, while the tail binds to linker DNA and neutralizes its negative charge.
- It is uncertain whether H1 promotes a solenoid-like chromatin fiber, in which exposed linker DNA is shortened, or whether it merely promotes a change in the angle of adjacent nucleosomes, without affecting linker length.
- It's difficult to find linker dna in a sentence. 用linker dna造句挺难的
- Nucleosomes, with about 20 to 60 base pairs of linker DNA, can form, under non-physiological conditions, an approximately 10 nm " beads-on-a-string " fibre . ( Fig . 1-2 ) ..
- Once the wave reaches the end of the histone octamer the excess that was once at the edge is extended into the region of linker DNA . In total, one round of this method moves the histone octamer several base pairs in a particular direction away from the direction the wave propagated.
- Histone H1 was shown to stabilize the structure by winding two turns of linker DNA around the octamer while HMGB1 destabilized the nucleosome by bending adjacent DNA . NMR spectroscopy was again used to show that H1 binds to the acidic tail of HMGB1 via its basic C-terminus, thus halting the HMGB1-DNA interaction.